Along with the announcement of the new Obi-Wan Kenobi show on Disney +, we were also given a broken down timeline of the official Star Wars Canon.
As per my previous post about the Obi-Wan reveal, the show will be set right after the end of Revenge of the Sith and before the events of Star Wars: Rebels. The image below breaks down the full timeline and also includes The Mandalorian show too.

The new timeline puts the show in the middle of the timeline for the Solo movie, and given the events of the end of that movie, could pit Obi-Wan against an old nemesis .